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Pediatr Infect Dis J ; 40(7): e263-e265, 2021 07 01.
Article in English | MEDLINE | ID: covidwho-1228551

ABSTRACT

COVID-19 spread globally and caused over 97 million cases with more than 2 million deaths. There is still ongoing discussion on the duration of infectious interval SARS-CoV-2 infection. Symptomatic children had longer virus shedding and there are some reports of prolonged infectious virus shedding in adults particularly patients having an immunocompromised status. A missense mutation, D614G, in the spike protein of SARS-CoV-2, which has emerged as a predominant clade in Europe and is spreading worldwide that can result in higher viral loads in patients. Herein, we described the longest infectious virus shedding in a previously healthy child infected with SARS-CoV-2 expressing spike D614G substitution.


Subject(s)
COVID-19/virology , Mutation, Missense , SARS-CoV-2/genetics , Virus Shedding , Adolescent , COVID-19/complications , COVID-19/diagnosis , Carrier State/virology , Humans , Immunocompetence , Male , Risk Factors , SARS-CoV-2/pathogenicity , Viral Load
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